The CRTAM Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD355, and CRTAM. This antibody recognizes Human, Mouse, and Rat antigen. The CRTAM Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo